Running Head: Impaired Ventilatory Efficiency/Exercise Intolerance in SmokersĪbbreviations: preserved ratio-impaired spirometry, PRISm forced expiratory volume in 1 second, FEV 1 chronic obstructive pulmonary disease, COPD minute ventilation, VE carbon dioxide production, VCO 2 cardiopulmonary exercise testing, CPET partial pressure of CO 2, PaCO 2 volume of oxygen consumed, VO2peak diffusing capacity of the lungs for carbon monoxide, DLCO Canadian study of Chronic Obstructive Lung Disease, CanCOLD computed tomography, CT modified Medical Research Council, mMRC maximal oxygen consumption, VO 2max COPD Assessment Test, CAT Global initiative for chronic Obstructive Lung Disease, GOLD carbon monoxide transfer coefficient, KCO ventilation/perfusion, V/QĬitation: Balkissoon R, Mkorombindo T.
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